Asthma Allergy Immunology

Asthma Allergy Immunology

2014, Vol 12, Num, 2     (Pages: 117-121)

A case of atypical urticarial vasculitis associated with thrombosis

Sakine IŞIK 1, Zeynep ARIKAN AYYILDIZ 1, Şule ÇAĞLAYAN SÖZMEN 1, Erdener ÖZER 2, Özkan KARAMAN 1, Nevin UZUNER 1,

1 Department of Pediatric Allergy and Immunology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey
2 Department of Pathology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey

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Urticarial vasculitis is characterized by pruritic, burning or painful, erythematous or edematous, circumscribed wheals with induration. It is most commonly idiopathic and it can occur in association with autoimmune disease, drug reactions, infections, or malignancy. Three forms of urticarial vasculitis has been described. These are normocomplementemic urticarial vasculitis, hypocomplementemic urticarial vasculitis, and hypocomplementemic urticarial vasculitis syndrome. We present a 17-year-old boy with urticarial vasculitis who has atypical lesions and venous thrombosis that related with Factor V Leiden mutation.

Keywords : Atypical, factor V Leiden, normocomplementemic, thrombosis, urticarial vasculitis