Asthma Allergy Immunology

Asthma Allergy Immunology

2014, Vol 12, Num, 1     (Pages: 001-008)

Allergic bronchopulmonary aspergillosis (ABPA)

Dilara Fatma KOCACIK UYGUN 1, Serkan FİLİZ 1, Ayşen BİNGÖL 1,

1 Akdeniz Üniversitesi Tıp Fakültesi, Pediatrik İmmünoloji ve Allerji Bilim Dalı, Antalya, Türkiye

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Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease of asthmatic or cystic fibrosis patients. It is a hypersensitivity reaction to Aspergillus fumigatus. Genetic factors, CD4 + Th2 lymphocyte activation and spesific antibodies production are responsible for the development of the disease. The diagnosis of ABPA is a combination of clinical, biological and radiological criteria. The treatment consists of oral corticosteroids and itraconasole. In this article, we review the diagnosis and treatment of ABPA according to recent investigations.

Keywords : Allergic bronchopulmonary aspergillosis, asthma, diagnosis, treatment