Asthma Allergy Immunology

Asthma Allergy Immunology

2016, Vol 14, Num, 2     (Pages: 093-097)

The Importance of Diagnostic Tests in Delayed Type Beta-Lactam Allergy: A Case Report

Deniz Özçeker 1, Dilek Kürkçü 2, Özge Umur 3, Ali Genco Gençay 3, Zeynep Tamay 1, Nermin GÜLER 4,

1 İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Çocuk İmmünolojisi ve Alerji Bilim Dalı, İstanbul, Türkiye
2 İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Çocuk Metabolizma ve Beslenme Bilim Dalı, İstanbul, Türkiye
3 İstanbul Üniversitesi, İstanbul Tıp Fakültesi,Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, İstanbul, Türkiye
4 İstanbul Bilim Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, İstanbul, Türkiye

DOI: 10.21911/aai.5018
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Adverse reactions to drugs have been defined by the WHO as unwanted effects that occur during the use of a drug. The diagnosis of drug allergies is not always straightforward due to confounding factors such as the use of multiple drugs and similarity of the pertinent symptoms to those that can be attributed to disease processes. In children, drug allergies are most commonly mistaken for rashes induced by viral infections. The first step towards the diagnosis of drug allergies is a detailed history and the second step is choosing a laboratory test according to this history. Skin prick testing is preferred for immediate type reactions while skin patch testing should be performed for delayed type reactions. When allergy tests are negative, drug provocation testing is the gold standard. In this paper, a case with a negative skin patch test that was ultimately diagnosed through a provocation test is presented.

Keywords : Dug allergy, delayde type drug allergy, skin prik test, oral provacation test