Asthma Allergy Immunology

Asthma Allergy Immunology

2017, Vol 15, Num, 1     (Pages: 049-054)

A Case of Acute Generalised Exanthematous Pustulosis Induced by Paracetamol

Şeyhan KUTLUĞ 1, Mehmet Halil ÇELİKSOY 1, Betül EROĞLU 2, Levent YILDIZ 3, Alişan YILDIRAN 1,

1 Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları AD, Çocuk İmmünoloji ve Allerji Bilim Dalı, Samsun, Türkiye
2 Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Samsun, Türkiye
3 Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Samsun, Türkiye

DOI: 10.21911/aai.5007
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Acute generalized exanthematous pustulosis is an exanthematous disease characterized by a great number of pustules on an acutely erythematous and edematous surface on the skin. These pustules are smaller than 5 mm, have non-follicular localization, and are sterile and superficial. Drugs are held responsible for 90% of the cases and antibiotics are the main culprits. Viral infections, mercury exposure, spider bite and radiation have also been rarely reported as the causative agent. The mortality of AGEP, which is considered to be one of the Severe Cutaneous Adverse Reactions (SCAR), is 5%. Many of the cases reported are adults. Since AGEP is rare in children, we present a ten-month-old boy who developed AGEP after paracetamol use.

Keywords : Drug allergy, paracetamol, child