Asthma Allergy Immunology

Asthma Allergy Immunology

2018, Vol 16, Num, 3     (Pages: 171-174)

Anaphylaxis Developoing after Measles Vaccine in an Infant with Cow`s Milk Allergy

Pınar UYSAL 1, Şenol ALAN 2, Faruk DEMIR 1, Duygu ERGE 1, Ayşe YENIGÜN 1,

1 Adnan Menderes Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları AD, Allerji ve Klinik İmmunoloji BD, Aydın, Türkiye
2 Bülent Ecevit Üniversitesi, Fen-Edebiyat Fakültesi, Genel Biyoloji Anabilim Dalı, Biyoloji Bölümü, Zonguldak, Türkiye

DOI: 10.21911/aai.175
Viewed: 127
 - 
Downloaded : 52

Cow`s milk allergy is the most common food allergy in children. Casein, whey, alpha-lactalbumin, beta-lactoglobulin and bovine gamma-globulin are the best known allergens in cow`s milk. Herein, we present an infant who was diagnosed with severe cow`s milk allergy, followed-up with an elimination diet, and experienced a life-threatening severe anaphylaxis after live attenuated measles vaccine containing alpha-lactalbumin hydrolysate. High levels of immunoglobulin E (IgE) antibodies were determined by specific IgE analysis and the sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) method. It might be dangerous to administer live attenuated measles vaccine to children diagnosed with cow`s milk allergy or to children suspected of being highly sensitive to cow`s milk proteins.

Keywords : Vaccine, alpha-lactalbumin, anaphylaxis, cow`s milk allergy, measles