Asthma Allergy Immunology

Asthma Allergy Immunology

2018, Vol 16, Num, 1     (Pages: 053-055)

Triptorelin Acetate-Related Anaphylaxis in a Child with Central Precocious Puberty: Case Report

Seda ŞIRIN KÖSE 1, Suna ASILSOY 1, Ece BÖBER 2, Nevin UZUNER 1, Özkan KARAMAN 1,

1 Dokuz Eylül Üniversitesi Tıp Fakültesi, Çocuk İmmünoloji ve Alerji Bilim Dalı, İzmir, Türkiye
2 Dokuz Eylül Üniversitesi Tıp Fakültesi, Çocuk Endokrinolojisi Bilim Dalı, İzmir, Türkiye

DOI: 10.21911/aai.53
Viewed: 865
Downloaded : 517

Anaphylaxis is an acute, potentially life-threatening allergic multisystemic hypersensitivity reaction. Although the anaphylaxis incidence is not clearly known, serious reactions are seen at a rate of approximately 1-3 per 10,000. Drugs are among the most common causes of anaphylactic reactions. Triptorelin acetate treatment aims to alleviate the clinical symptoms of early pubertal development, the psychological consequences and the effects on growth. Triptorelin acetate is major long-acting gonadotropin releasing hormone (GnRH) analogue. Our case diagnosed with central precocious puberty was being followed up by the pediatric endocrinology department when anaphylaxis occurred following an injection at the 18th month of treatment. Anaphylaxis with Triptorelin acetate has been reported in only two cases in the literature. Although the risk of anaphylaxis with this drug is low, the possibility should be considered and appropriate measures taken.

Keywords : Central precocious puberty, child, anaphylaxis, triptorelin acetate