Objective: In recent years, YouTube™, a social platform, has become a source used to access health-related information, but there are concerns about the accuracy and quality of the information in the content. In this study, we aimed to evaluate videos related to the use of subcutaneous immunoglobulin (SCIG) in terms of content, quality, understandability, and applicability.

Materials and Methods: On 06.02.2024, the keyword `How to use subcutaneous immunoglobulin` was typed into the YouTube™ (http://www.youtube.com) search bar in English and Turkish. Out of 101 videos, 31 (30:English, 1:Turkish) met the evaluation criteria. The videos were evaluated using the Modified DISCERN (mDISCERN), Global Quality Scale (GQS) and Patient Education Materials Assessment Tool (PEMAT-A/V). In addition, the steps of SCIG use were examined.

Results: A total of 30 English video recordings were evaluated in our study. The median mDISCERN score of the video content was 4 (range 1-5), the GQS score was 4 (range 2-5), and the PEMAT/A and PEMAT/V percentages were 85% (range 25-100) and 100% (range 33-100), respectively. The content was found to be 73.3% understandable. The median mDISCERN score (p=0.006), GQS score (p=0.004), and PEMAT/A percentage (p=0.025) of the videos uploaded by healthcare institutions were significantly higher than those of the videos uploaded by other content producers. Additionally, a positive correlation was found between video duration and mDISCERN score (r=0.459, p=0.011), GQS score (r=0.406, p=0.026), and PEMAT/A percentage (r=0.401, p=0.028). Three of the videos` contents included all SCIG usage steps. Only one of the videos in Turkish was about SCIG use.

Conclusion: There was a lack of SCIG use steps in the accessible video content. We believe that there is a need for videos that include complete usage steps by non-profit academic institutions and health professionals who are experts in this field regarding SCIG usage in our country and around the world.