Early detection of the etiologic agent is important in patients who present to the emergency department due to anaphylaxis, especially if the anaphylaxis is resistant. Even if there is no history of trauma in resistant anaphylaxis of unknown origin, hydatid cyst rupture should be considered since it is known that the hydatid cyst can rupture spontaneously.

A 15-year-old female patient presented to the emergency department of our hospital with complaints of widespread hot flashes, abdominal pain, and confusion during kickboxing training. Treatment of the patient was started with a preliminary diagnosis of anaphylaxis. Adrenaline infusion was started because of the refractory hypotension and lack of improvement in the clinical findings. The patient`s history was taken in more detail because of the resistant anaphylaxis. Abdominal ultrasonography was performed with the suspicion of hydatid cyst rupture due to the patient`s history of abdominal trauma while kickboxing. It was observed that the cysts were ruptured in the liver.

This case report emphasizes that hydatid rupture should be among the rare causes of anaphylaxis, especially in regions where hydatid disease is endemic. Ruptured hydatid cyst causing anaphylaxis requires timely diagnosis, treatment, and urgent intervention.