Fixed drug eruption is a common cutaneous reaction which may be seen in reaction to several medications. For the etiological evaluation of fixed drug eruption, topical provocation with patch testing on sites of previous lesions is frequently applied. Bullous fixed drug eruption mimicking toxic epidermal necrolysis due to a topical agent has not been previously reported. Here we describe a case of generalized bullous fixed drug eruption due to ibuprofen gel.