Objective: Drug allergies are drug-hypersensitivity reactions that are assumed to be seen frequently in practice and affect quality of life considerably. The aim of this study is to investigate the effect of drugallergy on quality of life.

Materials and Methods: A total of 100 patients, between 18-70 years of age, who referred to our center with drug allergy were evaluated prospectively. During assessment of patients, a questionnaire including socio-demographic characteristics and a Short Form-36 (SF-36) Quality of Life Scale were used.

Results: Of our patients 76% were women, 24% were males and mean age was 38.56 ± 11.03 years. The physical, social and emotional role components of SF-36 were found to be decreased in all areas in women. When the score dispersion of quality of life subscale according to education level was examined, the `physical function` subscale was found lower only in elementary school and lesser education areas.

Conclusion: In present study it was observed that drug allergy had affected the quality of life of both genders; however its influence over women was more prominent.