Asthma Allergy Immunology

Asthma Allergy Immunology

2018, Vol 16, Num, 3     (Pages: 175-178)

Successful Rapid Desensitization Protocol for Delayed Type Drug Eruption in a Patient Using Temozolamide

Ahmet KAN 1, Meltem AKGÜL 2, Arzu BAKIRTAŞ 1,

1 Gazi Üniversitesi Tıp Fakültesi, Çocuk Allerji ve Astım Bilim Dalı, Ankara, Türkiye
2 Gazi Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Ankara, Türkiye

DOI: 10.21911/aai.222
Viewed: 197
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Downloaded : 86

Despite rapid desensitization protocols classically applied to immediate hypersensitivity reactions, the number of case reports of rapid desensitization in delayed hypersensitivity is gradually increasing. Temozolamide is a chemotherapeutic agent used in the treatment of malignant glioma. The rapid desensitization protocol was performed successfully in a case with delayed skin eruptions after temozolamide treatment. This case shows that the rapid desensitization protocol can be an alternative safe and effective choice of treatment for delayed hypersensitivity reactions.

Keywords : Delayed hypersensitivity, rapid desensitization, temozolamide hypersensitivity, drug eruption