Successful Rapid Desensitization Protocol for Delayed Type Drug Eruption in a Patient Using Temozolamide

Ahmet Kan
Meltem Akgül
Arzu Bakırtaş

Abstract

Despite rapid desensitization protocols classically applied to immediate hypersensitivity reactions, the number of case reports of rapid desensitization in delayed hypersensitivity is gradually increasing. Temozolamide is a chemotherapeutic agent used in the treatment of malignant glioma. The rapid desensitization protocol was performed successfully in a case with delayed skin eruptions after temozolamide treatment. This case shows that the rapid desensitization protocol can be an alternative safe and effective choice of treatment for delayed hypersensitivity reactions.

Keywords

Delayed hypersensitivity, rapid desensitization, temozolamide hypersensitivity, drug eruption
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