Anaphylaxis Developoing after Measles Vaccine in an Infant with Cow’s Milk Allergy

Pınar Uysal
Şenol Alan
Faruk Demir
Duygu Erge
Ayşe Yenigün

Abstract

Cow’s milk allergy is the most common food allergy in children. Casein, whey, alpha-lactalbumin, beta-lactoglobulin and bovine gamma-globulin are the best known allergens in cow’s milk. Herein, we present an infant who was diagnosed with severe cow’s milk allergy, followed-up with an elimination diet, and experienced a life-threatening severe anaphylaxis after live attenuated measles vaccine containing alpha-lactalbumin hydrolysate. High levels of immunoglobulin E (IgE) antibodies were determined by specific IgE analysis and the sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) method. It might be dangerous to administer live attenuated measles vaccine to children diagnosed with cow’s milk allergy or to children suspected of being highly sensitive to cow’s milk proteins.

Keywords

Vaccine, alpha-lactalbumin, anaphylaxis, cow’s milk allergy, measles
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