Allergic Bronchopulmonary Aspergillosis (ABPA)

Dilara Fatma Kocacık Uygun
Serkan Filiz
Ayşe Bingöl

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disease of asthmatic or cystic fibrosis patients. It is a hypersensitivity reaction to Aspergillus fumigatus. Genetic factors, CD4 + Th2 lymphocyte activation and spesific antibodies production are responsible for the development of the disease. The diagnosis of ABPA is a combination of clinical, biological and radiological criteria. The treatment consists of oral corticosteroids and itraconasole. In this article, we review the diagnosis and treatment of ABPA according to recent investigations.

Keywords

Allergic bronchopulmonary aspergillosis, asthma, diagnosis, treatment
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